A Secret Weapon For ceesdekker.net
A Secret Weapon For ceesdekker.net
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‘Certainly, which is about suitable. I look for a Bodily idea of biological programs inside of a bottom-up way. I feel you could potentially distinguish three traces of exploration in my group in the intervening time. The very first problems chromosome composition: How can you get yourself a metre-extensive DNA polymer folded and organised in such a microscopic cell? We've got formulated visualisation techniques that permit us to review how, such as, SMC proteins loop DNA (online video on Youtube) to be able to Create up chromosomes.
Our team scientific tests bacterial mobile division and it is aiming to constitute a ‘bottom up biology’ in artificial cells which will autonomously divide. Our major curiosity lies in cell division, chromatin framework, and spatial Management.
Dynamics of initiation, termination and reinitiation of DNA translocation because of the motor protein EcoR124I
Our operate was promptly adopted up by Many others, most notably by Phaedon Avouris and colleagues at IBM, who in Oct 1998 posted their conclusions on transistors comprised of one- and multi-walled carbon nanotubes in Used Physics Letters.
This yielded a breakthrough. In just just a few months, we were ready to measure transportation by way of an individual solitary-walled carbon nanotube. According to very low-temperature experiments by a brilliant PhD student in my group, Sander Tans (now a valued colleague and professor at Delft College of Technological innovation with an Energetic research lab at AMOLF in Amsterdam), we showed that carbon nanotubes were being real quantum wires with pretty extended (micrometres) Digital coherence lengths — confirming theoretical predictions of metallic conduct.
Electrical transport in monolayers of phthalocyanine molecular wires and AFM imaging of only one wire bridging two electrodes
You're a Christian. If you might make such a artificial cell, would you be a person phase closer to God, or would the purpose of God have diminished relatively all over again?
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‘The fantastically delicate way during which components in mother nature purpose never ever ceases to amaze me. If we remedy the puzzle of how existence came into remaining, I be expecting that my amazement with the complexity of creation will have greater and with it my awe to the greatness in the Creator.’
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Cees Dekker is Distinguished College Professor at TU Delft. Trained as a physicist, he pioneered nanotechnology with many discoveries on carbon nanotubes in the nineteen nineties. Since 2000, he moved to one-molecule biophysics and nanobiology. His present-day investigate concentrates on (i) nanopores for protein sequencing; (ii) chromosome framework, specifically SMC motor protein; and (iii) creating a living artificial mobile from lifeless molecules. Dekker is really an elected member with the KNAW and fellow on the APS along with the IOP.
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Instance (two) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is demonstrated in grey, the rim on the pore is highlighted in red, and also a 3D rendering from the movement from the DNA rod is shown.